Actual Analytics were pleased to collaborate with leading experts on the following research: 'Identification of Altered Evoked and Non-Evoked Responses in a Heterologous Mouse Model of Endometriosis-Associated Pain'.
The study by Tejada et al., explored the use of a number of behavioural measurements in a mouse model for pain. They used a series of classic evoked assays in addition to non-evoked measurements using a nest building task and measurements taken from group housed animals in the Home Cage Analyser (HCA). They reported the effects on a range of behavioural biomarkers automatically measured by the HCA systems including locomotor activity, social interactivity, drinking and climbing. The most robust difference was time spent climbing which was shown to be reduced by around half in the pain model animals relative to their controls.